Afrezza: Extreme Glucose Challenge

This video is a follow-up to the Extreme Coke Challenge.

Using fast-acting emergency glucose with 5g more sugar than the can of coke, and a higher starting blood glucose level, we see how Afrezza deals with this unlikely situation. Afrezza is so fast it doesn’t need a head start. This video shows why Afrezza is less effective when taken before a meal, and should be taken at least 10 minutes after starting most meals.

It is of interest that the final glucose reading in Coke video at 85 minutes after drinking the coke was 6.0 mmol/L. In this video, the glucose reading was 6.4 mmol/L at 80 minutes after drinking the glucose. This is 0.4 mmol/L difference between the two videos, which is identical to the starting difference. This suggests the results would have stayed in the non-diabetic range if Afrezza was not taken in advance.

Update: It will be interesting to re-run this experiment without giving Afrezza a head start, and see how different the result is now that I have switched basal.

-Matt

The unedited video can be downloaded below.

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Afrezza: Extreme Coke Challenge

This impressive video demonstrates how Afrezza works very differently to previous treatments for Type 1 diabetes.

Although I’m only 3 weeks in and still working it all out, I’m beginning to see how Afrezza can really widen the range of foods I could eat while still improving my glucose control. This is the best demonstration I could think of to show off its capabilities. For non-diabetics, read this for real experiences of would happen without Afrezza.


I did this test on an empty stomach. I started at 11:57am, the only thing I had consumed was a coffee at 9:27am. For this I had the small Afrezza dose (blue), so there was no residual glucose lowering going on.

I couldn’t have done this even a week ago, and feel like I am getting better control of my diabetes and a better understanding of Afrezza every day.
Carbs: Ice-cream 15.2g + 375mL Coke 40g = TOTAL 55.2g sugar
Lantus: 7u AM, 9u PM – (before Afrezza, Lantus was 10u AM, 9u PM)

Also see a follow up experiment using emergency glucose here.

The unedited files can be downloaded below.

-Matt

Update: The results for this experiment may be even more impressive now that I have further optimised my basal insulin type and dose. Expect a re-run in the future.

 

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Afrezza and Lantus doses

This video is about basal insulin and the timing of Afrezza doses.

I wish I had known that Afrezza needed a basal dose adjustment, as previous insulins were pretty forgiving. Here’s an image which sums it up:

Afrezza and Excessive Lantus Doses

My previous Lantus dose when using Apidra was 9u in the morning and 10u in the evening, and I continued with that when starting Afrezza. But my glucose always seemed high, even though I was inhaling buckets of the stuff.

I thought it was that I needed more basal, but counterintuitively that made it even worse. I wanted to keep increasing it, but my partner insisted that lowering it might help. I said that’s impossible. But somehow it worked.

Later posts will cover optimising the Lantus dose split, switching to the more stable Levemir and Tresiba, and will explain what caused those blood glucose peaks.

Update: I later switched to Levemir, and am now using Afrezza with the amazing new basal Tresiba. I will soon post more info on these changes. This link will be updated once I have collected more data.